USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: TWF2_HUMAN USC-OGP 2-DE database:  TWF2_HUMAN TWF2_HUMAN General information about the entry View entry in simple text format Entry name TWF2_HUMAN Primary accession number Q6IBS0 Secondary accession number(s) Q9Y3F5 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Twinfilin-2; AltName: Full=A6-related protein; Short=hA6RP; AltName: Full=Protein tyrosine kinase 9-like; AltName: Full=Twinfilin-1-like protein;. Gene name Name=TWF2 Synonyms=PTK9L ORFNames=MSTP011 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0432: pI=6.42; Mw=40313 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0955: pI=6.32; Mw=40359 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1171: pI=4.97; Mw=46576 SPOT OGP-1195: pI=6.77; Mw=40578 Cross-references UniProtKB/Swiss-Prot Q6IBS0; TWF2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TWF2_HUMAN Primary accession number Q6IBS0 Secondary accession number(s) Q9Y3F5 Sequence was last modified on  May 2, 2006 (version 2) Annotations were last modified on  March 15, 2017 (version 124) Name and origin of the protein Description RecName: Full=Twinfilin-2; AltName: Full=A6-related protein; Short=hA6RP; AltName: Full=Protein tyrosine kinase 9-like; AltName: Full=Twinfilin-1-like protein; Gene name Name=TWF2 Synonyms=PTK9L ORFNames=MSTP011 Encoded on Name=TWF2; Synonyms=PTK9L; ORFNames=MSTP011 Keywords 3D-structure; Acetylation; Actin-binding; Cell projection; Cilium biogenesis/degradation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Phosphoprotein; Polymorphism; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Y17169; CAB38055.1; -; mRNA EMBL AL136773; CAB66707.1; -; mRNA EMBL AF109365; AAQ13513.1; -; mRNA EMBL CR456732; CAG33013.1; -; mRNA EMBL CR533520; CAG38551.1; -; mRNA EMBL BC000327; AAH00327.1; -; mRNA EMBL BC003161; AAH03161.1; -; mRNA EMBL BC016452; AAH16452.1; -; mRNA CCDS CCDS2849.1; -; . PIR T46362; T46362; . RefSeq NP_009215.1; NM_007284.3; . UniGene Hs.436439; -; . PDB 2VAC; X-ray; 1.70 A; A=6-137 PDB 2W0I; X-ray; 1.80 A; A=181-313 PDBsum 2VAC; -; . PDBsum 2W0I; -; . ProteinModelPortal Q6IBS0; -; . SMR Q6IBS0; -; . BioGrid 116472; 63; . IntAct Q6IBS0; 14; . MINT MINT-1414584; -; . STRING 9606.ENSP00000303908; -; . iPTMnet Q6IBS0; -; . PhosphoSitePlus Q6IBS0; -; . SwissPalm Q6IBS0; -; . BioMuta TWF2; -; . DMDM 94730596; -; . OGP Q9Y3F5; -; . EPD Q6IBS0; -; . MaxQB Q6IBS0; -; . PaxDb Q6IBS0; -; . PeptideAtlas Q6IBS0; -; . PRIDE Q6IBS0; -; . DNASU 11344; -; . Ensembl ENST00000305533; ENSP00000303908; ENSG00000247596; . GeneID 11344; -; . KEGG hsa:11344; -; . UCSC uc003ddd.4; human; . CTD 11344; -; . GeneCards TWF2; -; . HGNC HGNC:9621; TWF2; . HPA HPA053874; -; . MIM 607433; gene; . neXtProt NX_Q6IBS0; -; . OpenTargets ENSG00000247596; -; . PharmGKB PA162407429; -; . eggNOG KOG1747; Eukaryota; . eggNOG ENOG410XS1J; LUCA; . GeneTree ENSGT00530000063868; -; . HOGENOM HOG000168296; -; . HOVERGEN HBG000848; -; . InParanoid Q6IBS0; -; . KO K08870; -; . OMA IRLIKVI; -; . OrthoDB EOG091G0BWK; -; . PhylomeDB Q6IBS0; -; . TreeFam TF352598; -; . EvolutionaryTrace Q6IBS0; -; . GeneWiki TWF2; -; . GenomeRNAi 11344; -; . PRO PR:Q6IBS0; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000247596; -; . CleanEx HS_TWF2; -; . ExpressionAtlas Q6IBS0; baseline and differential; . Genevisible Q6IBS0; HS; . GO GO:0005737; C:cytoplasm; NAS:UniProtKB; . GO GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0030175; C:filopodium; ISS:BHF-UCL; . GO GO:0030426; C:growth cone; IDA:BHF-UCL; . GO GO:0030027; C:lamellipodium; ISS:BHF-UCL; . GO GO:0030016; C:myofibril; ISS:BHF-UCL; . GO GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL; . GO GO:0032420; C:stereocilium; ISS:BHF-UCL; . GO GO:0003785; F:actin monomer binding; ISS:BHF-UCL; . GO GO:0005524; F:ATP binding; IDA:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0005546; F:phosphatidylinositol-4; 5-bisphosphate binding; ISS:BHF-UCL GO GO:0005080; F:protein kinase C binding; IPI:BHF-UCL; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0051016; P:barbed-end actin filament capping; ISS:BHF-UCL; . GO GO:0030030; P:cell projection organization; IEA:UniProtKB-KW; . GO GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL; . GO GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL; . GO GO:0030837; P:negative regulation of actin filament polymerization; ISS:BHF-UCL; . GO GO:0045773; P:positive regulation of axon extension; IMP:BHF-UCL; . GO GO:0010592; P:positive regulation of lamellipodium assembly; IMP:BHF-UCL; . GO GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL; . GO GO:0032956; P:regulation of actin cytoskeleton organization; IMP:BHF-UCL; . GO GO:0032532; P:regulation of microvillus length; IC:BHF-UCL; . GO GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL; . Gene3D 3.40.20.10; -; 2; . InterPro IPR002108; ADF-H; . InterPro IPR029006; ADF-H/Gelsolin-like_dom; . InterPro IPR028458; Twinfilin; . PANTHER PTHR13759; PTHR13759; 1; . Pfam PF00241; Cofilin_ADF; 2; . SMART SM00102; ADF; 2; . PROSITE PS51263; ADF_H; 2; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]